national news today: February 2012

Wednesday, February 29, 2012

Free Design Tutorials: 15 + Graphics Design Tutorials | Best Graphic ...

Graphic design tutorials, which are designed by experts, consist of drawings and pictures that an aspiring designer needs for presenting different works. A tutorial at first ensures to strengthen the base for a designer, and also introduces him to different lines, textures, shapes, color and mass. It makes him familiar with the function of each designing element. Here we collected Free Design Tutorials: 15 + Graphics Design Tutorials.

Create a Planetary Asteroid Impact ? Psd Premium Tutorial

While asteroids don?t slam into the Earth all that often, movie producers sure act like they do. We can all think up a few movies with similar plots. An asteroid is about to hit the planet and a group of heroes comes to save the day. In this Psd Premium tutorial, author Ed Lopez will demonstrate how to create an asteroid impact, just like in the movies. If you would like to take your Photoshop skills to the next level, Log in or Join Now to get started!

Create Awesome Abstract Illustrations Using Stock Art From Visual Freaks

Some people might not realize how fun and easy it can be to create an awesome illustration with just a few pieces of stock art elements. In today?s tutorial we will demonstrate how to create an abstract illustration using a few pieces of stock art from Visual Freaks? Organic CG Art Pack and just some basic knowledge of Photoshop. Let?s get started!

Design and Print a Skateboard Deck and T-Shirt ? Psd Premium Tutorial

Today?s Psd Premium tutorial by author Mark Mayers will focus on creating a brand for a fictitious skate company and also applying graphics to a skate deck and T-shirt. We?ll demonstrate how to achieve professional results every time ? both items were actually printed using the tutorial techniques. For screen-print fanatics, there?s an extra bonus; you?ll discover how the Apply Image command enables you to create knockouts and error-free spot colors without the need for expensive RIP software. Special thanks to Steve over at Advertees for printing the shirts and providing invaluable technical advice. This tutorial is available exclusively to Premium Members. If you are looking to take your print and t-shirt design skills to the next level then Log in or Join Now to get started!

Design? Coffee Shop Menu Layout from Scratch with Photoshop and InDesign ? Part 1

Hi everyone, this time I?ve got for you a practical tutorial about creating a ready to print booklet menu for an imaginary coffee shop named ?Violet Coffee.? In this tutorial you?ll learn to mockup a ready to print background and a couple of additional objects, which will be imported later on in Adobe InDesign to finish the piece. Are you ready?

Use Photo Manipulation and 3D Layers to Design a Surreal Cover Art Illustration

My clients often ask me to create impossible scenarios, weird landscapes and surreal images for their projects; images that wouldn?t be possible in real life. It?s situations like these where photo manipulation becomes a powerful design tool. In today?s tutorial I will show you how to design a CD cover using several photo manipulation techniques, how to keep critical text layers editable for any future change and how to render a quick mockup using the Vanishing Point filter. Let?s get it started!

How to Create an Ice-cold Poster with 3D Text

In this tutorial, you?ll learn how to combine stock images and 3D text into a cool poster. We?ll use an icy theme for it and color it the way we want. You?ll see it?s not that hard to create a simple appealing poster with effective use of text and imagery.

Dynamic Recessed Watercolor Typography in Photoshop

In this tutorial, I?ll show you how to mix vector elements and watercolor effects with text to create a stunning design. It?s a quick process that depends heavily on good choices of images and colors.

Make a Turn of the Century Vaudeville Poster

In this tutorial, we?ll learn how create a turn-of-the-century Vaudeville poster. This uniquely appealing style of advertisement was popular in the late 1800s and early 1900s. You sir! You madam! Step right up and prepare to be amazed as we transport an image of two friends back in time to create a poster advertisement without compare!

Create a Realistic Blackberry Style Mobile Phone From Scratch

If you ever have to create a slick phone or Blackberry design, and you don?t feel like buying stock images, then this tutorial is for you. I will show you how to use Vector Shapes, Masks, and mostly Layer Effects to create this elegant design.

Create a Cool Music Logo on a Grunge Background

I really like the artwork that is used in Pitchfork?s Web site, so I decided to recreate something similar in Photoshop and make a tutorial on how I did it. These techniques can be used to make a logo and background for a cool grunge-style Web site.

Quick Grungy Poster

In this tutorial, I will show you how to create a sort of grunge poster. We will learn how to make some elements look a bit dirty, create textures, and add some depths to the elements using shadows and blend modes.

Create A Cool Vintage Collage Design In Photoshop

In this tutorial, I will show you how to create a retro-style design or vintage collage style. We will use images from old ads, handwritten texts, patterns, and other things to give to our design a vintage look.

Creating an Old-Collage Effect Poster

One of my favorite ?looks? is the sort of old-collage feel of old photos and old paper. It?s a favorite because it lets you work images and text together really easily. In this tutorial we?ll put together a poster where there is a main photograph and a lot of text using the old-collage feel.

Creating a Stunning Old-World Look in Photoshop

In this tutorial, we are going to create a sort of old-worldy composition featuring a compass and making use of some awesome vector artwork from Arsenal. As always there is a PSD file at the bottom of the tutorial. In this instance, I would highly recommend downloading it as this is quite a complex composition. Be warned this is a LONG tutorial!

Elements of Great Web Design: The Polish

When I put together designs, I usually do so in two phases ? Layout and Polish. During the layout phase, I place the main objects on the page usually finishing with something that looks relatively complete. In the second stage ? the Polish ? I go over the design and adjust colors, type treatments, shadows, layers, and generally clean it all up. In this first of a series of tutorials on web design, we?ll be looking at the Polish.

How to create Neon Illustration Happy New Year 2012 in Photoshop CS5

In this tutorial, we are going to design a simple New Year illustration with neon digits in Photoshop CS5. I hope you enjoy this tutorial and that it inspires you to create your own illustration for New Year! Layered PSD file included. Let?s get started!

How to stylise model shoot using colourful shapes in Photoshop

Start working by creating a new document (Ctrl+N) in Adobe Photoshop with the size 1280px by 1024px (RGB color mode) at a resolution of 72 pixels/inch. Use the Paint Bucket Tool (G) to fill with black color the new background layer

How to design an abstract Christmas illustration with colorful shapes and glass baubles in Photoshop CS5

We have another great tutorial available for our readers today. If you want to learn how to design an abstract Christmas illustration with colorful shapes and glass baubles, using simple shapes and gradients in Adobe Photoshop CS5, then this tutorial is for you.

Mac ? Colorful Design

For the beginning we need to create a new file of 1600?1200 px and 72 dpi. After that create another file of 4?4 px and 72 dpi too. Using the Pencil Tool (B), let?s represent a kind of block, like the next one. The color?s codes for the new elements are shown below.

Source: http://best-graphicdesign.com/2012/02/free-design-tutorials-15-graphics-design-tutorials/?utm_source=rss&utm_medium=rss&utm_campaign=free-design-tutorials-15-graphics-design-tutorials

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AT&T announces global coverage via a single SIM at MWC, makes dual-wielding a thing of the past

Tired of switching out those SIM cards when you travel abroad? AT&T is about to relieve that burden. At MWC, the company has announced a new platform that offers global internet, WiFi, satellite and Ma Bell network coverage via a single SIM. In addition to the hardware, the new tech offers worldwide diagnostic, monitoring and alert / response features for management purposes from AT&T Control Center -- backed by Jasper Wireless. Glenn Lurie, President of Emerging Segments notes "Lessons learned by market leading manufacturers suggest that a single carrier supplier with a single SIM solution is often preferred over working directly with multiple regional wireless carriers." Coverage for globetrotters will be provided in more than 200 countries via hundreds of carriers to keep you connected -- with a few less components in tow. If you're looking for a few more details, hit the full PR below to read on.

Continue reading AT&T announces global coverage via a single SIM at MWC, makes dual-wielding a thing of the past

AT&T announces global coverage via a single SIM at MWC, makes dual-wielding a thing of the past originally appeared on Engadget on Mon, 27 Feb 2012 09:28:00 EDT. Please see our terms for use of feeds.

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Tuesday, February 28, 2012

The Heart's Health Standards of Fitness and Fatness

It is a well established fact that fitness does play a huge role in keeping one?s health in check. The sad part is that people often times see fitness as something to be dived into by those who only want to stay slim, sexy and maintain or even form their six pack abs. Hence, majority of those filling in gym schedules are those who want to shed away those excess fats to turn their body waistline from an eight to a perfect size two. This has been one of the sad truths on how people perceive the value of fitness into their health and into their lives. Medical health researchers have come public to box out these pre-conceived stereotyped ideas with regards to fitness and establish a new definition for it. In truth, fitness and fatness holds the key health to a person?s heart and this would be explained further by this entry.

When a person ages, it is quite important to keep their fitness and weight gain in check. This is all because a decrease in fitness as well as accumulating more fat into the system would cause numerous problems to the pumping circulatory machine of the body. Researchers have delved into the deeper association of fitness and fatness with the heart?s condition. Studying a population of more than 3,100 healthy adult subjects, researchers have found out that those who keep improved or maintained their fitness levels were found to have less risk in developing heart diseases such as high blood pressure and high cholesterol compared to those who are slim or fat without keeping up their body fit or be active in a fitness routine. Such result was also seen in people who kept their weight in check regardless of fitness issue. Researchers have brought the truth that increased fitness levels over time do counter some of the ill effects of weight gain which eventually cause more heart and other problems to a particular person. At the very same time, losing touch with fitness is not a sin as long as people do keep their weight in moderation or maintain a healthy and proportional body weight with their height. Surely, with such results, researchers do emphasize to the public that keeping the heart in a healthy shape is not that difficult at all.

For overweight people, the best combination that you could adapt in your daily routine is to try to lose weight and increase your fitness level. If this is quite difficult to do or achieve (which it is!), then try maintaining your weight or fitness levels instead. Those who did not actually live to do such routine and stayed in their average unhealthy lifestyle did developed high blood pressure at a rate of four percent a year, high cholesterol at a rate of three percent a year and other metabolic syndrome at a rate of two percent a year. All this collecting of heart problems occurred in the span of six years. On the other hand, those participants who kept improving their fitness level as seen through a treadmill test, had lower incidence of acquiring such diseases. Specifically, they had 26% ? 30% lower risk of high blood pressure or high cholesterol and 42% ? 52% lower. The people who increased their percentage of body fat overtime, on the other hand, did develop heart risk factors and problems. In this description of results, researchers would like to reveal the evil truth that for every percent increase in a person?s body fat, there is three to eight percent increase in risk factors affecting one?s heart.

So, join the group of people who despite gaining weight but still maintained their fitness levels and be free of all the risk factors that would lead you into having a heart attack during your middle to old age years. For those people who are active, do stay active. For overweight people, do not despair as you can compensate for the weight by increasing your fitness. For those who exercise, continue to do so. Lastly, for those with sedentary lifestyle, try to do at least a fifteen to thirty minute brisk walking activity. Get the right fitness and weigh the right fatness and give your heart a healthy life in the process!

Technorati Tags: Fatness, fitness, health, Heart, Standards

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Source: http://weightlossrevolution.net/the-hearts-health-standards-of-fitness-and-fatness

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MO Workers' Comp Co. Profits From Best-of-Both-Worlds Scenario ...

JEFFERSON CITY, Mo. (AP) A state-created insurance company has built a competitive advantage by enjoying a best-of-both-worlds scenario avoiding federal income taxes by claiming to be a public corporation yet generally operating as a private entity and shelling out big bucks for executive perks, according to a report Monday by the Missouri auditor.

The federal tax-exempt status has saved Missouri Employers Mutual Insurance Co. an estimated $50 million since it was created under a 1993 state law, helping it to build a surplus of more than $160 million and become a dominant workers? compensation insurance provider in Missouri, Auditor Tom Schweich said. The Columbia-based firm qualifies for the tax break by categorizing itself as an ?independent public corporation.?

But MEM denies it is a public entity subject to Missouri?s open-records-and-meetings law or the state auditor?s office. Schweich recommended that lawmakers clarify whether it is appropriate for MEM to continue as a ?public corporation? and, if so, whether restrictions should be imposed on employee pay and expenses.

?It is sort of a situation of having your cake and eating it too, but it?s not illegal as long as the Legislature wants that,? Schweich said.

The company said in a written statement attached to Schweich?s report that it voluntarily agreed to a one-time review by the auditor?s office ?to clearly demonstrate that the company has proper internal controls in place.?

Although Schweich?s review found no significant problems with the company?s internal controls, it said the company needs to improve its management practices. Schweich cited several cases of employee salaries, bonuses, severance payments, expenses and junkets that he said would be excessive or unreasonable for a public entity. For example, the company:

Paid nearly $1.6 million in severance or settlement payments to four former employees who resigned or were fired in 2009 or 2010 under employment agreements that Schweich said may have violated the Missouri Constitution.

Spent more than $300,000 on a ?President?s Trip? for 64 people to go to Lanai, Hawaii, in February 2010. Attendees included top insurance agency performers as well as company executives and board members and their guests.

Spent about $90,000 on suites and tickets to St. Louis Cardinals and University of Missouri athletics events in 2010, including some suite tickets purchased through an associate of a former board member that went unused.

Contributed $8,000 to the Missouri Democratic Party, and $4,000 for gubernatorial inaugural festivities in 2005 and 2009. The company also contributed $5,000 to inaugural events in 2001, though that?s not noted in the audit because the review did not go back that far.

Some of the expenses were noted by an internal company investigation, the results of which were made available to auditors. The audit said MEM is pursuing reimbursement of the political contributions and a refund of unused Cardinals tickets, and has taken several confidential personal actions.

CEO Jim Owen said Monday that he could not discuss the political contributions because they are part of a federal investigation. Schweich said he also had agreed with the FBI not to elaborate on the contributions. The Kansas City Star first reported last September that investigators were focusing on whether money was funneled from MEM or its then-CEO, former Gov. Roger Wilson through a law firm to the Democratic Party.

Owen defended the company?s expenses for trips and sports tickets as an essential part of the insurance business. But Owens added that, under his leadership, MEM has significantly scaled back its annual president?s outing holding the last two in Branson and Columbia.

The auditors ?think we should be paying salaries and compensation of a state agency but, if we did that, we never would have been in business and wouldn?t have been able to have solved the workers comp crisis in Missouri,? Owens said.

The company said its federal tax advantage is offset by additional operating costs it must incur under the state law. Unlike most private insurers, MEM said it must give preference to small business owners with annual premiums not to exceed $10,000 and must implement work safety programs for all of its policyholders.

The company recently has undergone a couple rounds of executive turnover. Its first CEO, former state Sen. Dennis Smith, retired in 2009 and was succeeded by Wilson, who was placed on administrative leave and then removed from the position in 2011. Owen, who had been the board chairman, took over as interim CEO following Wilson?s departure and was permanently named to the job in December.

Two former MEM board members also faced federal indictments last year. Former chairman Douglas D. Morgan was indicted in April on allegations he defrauded a bank in a casino deal. Morgan, who was ill, died in November before going to trial. Former board member Karen Pletz was charged last March with embezzling more than $1.5 million from the Kansas City medical school where she was president. Pletz died in November in Florida in what a coroner ruled was a suicide.

Source: http://stlouis.cbslocal.com/2012/02/27/mo-workers-comp-co-profits-from-best-of-both-worlds-scenario/

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Monday, February 27, 2012

We're eating out less, opting for chains more

Andrew Gombert / EPA

Chain restaurants are faring better than indepdendents lately.

By Allison Linn

Think of the last time you went out to eat, and be honest: Did you chow down at a favorite locally owned haunt, or opt for the familiarity of a chain restaurant?

A new report from market researchers NPD Group finds that overall, Americans are eating out less than? few years ago, as the weak economy has caused people to cut back on such splurges. Total restaurant visits have fallen every year since 2008, from 62.7 billion restaurant visits that year to 60.6 billion in 2011.

The cutbacks have hit mom-and-pop restaurants much harder than chains. The NPD Group data shows that independent restaurants now account for 27 percent of restaurant visits, down from 28 percent in 2008.

When business falls, closures are inevitable. Although the number of independent restaurants increased slightly between 2008 and 2009, many independent restaurateurs have since had to throw in the towel.

In the past two years, NPD reports that the number of independent restaurants in the U.S. has fallen by 8,652. In that same two-year period, the number of chain restaurants has increased by 1,750.

Do you tend to eat out at chain or indepdendent restaurants?

Source: http://lifeinc.today.msnbc.msn.com/_news/2012/02/27/10519020-were-eating-out-less-and-opting-for-chains-more

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Boys Town founder touted for sainthood

OMAHA, Neb.?? The Omaha Archdiocese is launching a campaign for sainthood for Father Edward J. Flanagan, the Catholic priest who founded Boys Town and whose story was immortalized by an Academy Award-winning movie.

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Flanagan dedicated much of his life to ministering to orphans and troubled youth, and is best remembered for establishing in 1917 the Omaha orphanage Father Flanagan's Boys Home.

The archdiocese will formally open the canonization process -- which is often lengthy -- with a March 17 prayer service at Boys Town's Immaculate Conception Church.

Flanagan, who died in 1948, was known for believing that every child could be a productive citizen if given love, a home, an education and a trade, and accepted boys of every race and creed. He is quoted as saying, "There are no bad boys. There is only bad environment, bad training, bad example, bad thinking."

His story was told in the 1938 film, "Boys Town," starring Spencer Tracy, who won a best actor Oscar for his portrayal of Flanagan.

The canonization process to sainthood starts in the archdiocese and goes to the Congregation of the Causes of Saints in Rome and to the pope. To be canonized a saint, at least two miracles associated with Flanagan must have been performed after his death.

Reverend Steven Boes, national executive director of Boys Town, said in a statement that Flanagan is receiving recognition he deserves.

"Though the process will be investigating proven miracles associated with Father Flanagan, we know that miracles occurred every day in his work to heal children in mind, body and spirit," he said. "These everyday miracles still occur as Boys Town continues Flanagan's work by saving children and healing families today."

Flanagan was born in 1886 in County Roscommon, Ireland. He came to the United States in 1904 and was ordained in 1912. He toured the United States discussing his views on juvenile delinquency.

After World War Two, President Harry Truman asked Flanagan to travel around the world for discussions about children orphaned and displaced by the war. During a tour of Europe, he died of a heart attack in Berlin, Germany, on May 15, 1948. He is buried in the chapel at Boys Town.

The canonization process has the potential to inspire the more than 230,000 Catholics in northeast Nebraska, said Deacon Tim McNeil, chancellor of the archdiocese, in a statement.

"If Father Flanagan becomes sainted, it would send a message to Nebraskans," McNeil said. "If he could live a holy and exemplary life in Omaha, why can't we all?"

Source: http://www.msnbc.msn.com/id/46525073/ns/us_news-life/

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Sunday, February 26, 2012

socialmeteor: Cassidy: Will Facebook, Twitter, Fundly and the like be the fundraisers of the future? - San Jose... http://t.co/4uFqplzD #socialmedia

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The Infant Boomer Singles Scene

The 1960?s was full of multifaceted time landmarks forever etched ever. Consequently, social activities and political discourses were commonplace, especially to teenagers. Thus, these flourishing youths were (but still are) considered to be great in interacting and relevant with others, given their participation in social actions or causes. Presuming that each youthful adult in this time around frame was socially interactive, baby seniors who?re still single today might have an extremely easy time participating in the middle age dating scene.

Those who are an element of the baby boomer generation possess a lot opting for them. Lots of people of the age possess the predisposition to remain healthy physically, psychologically and socially. Consequently, you will find many great activities that may be converted into great dating possibilities for those who are middle age.

Middle age dating choices for baby seniors

Based on various US sporting associations, you will see an obvious rise in the amount of grown ups, especially from the generation from the seniors, who get some exercise regularly and participate in sports and leisure possibilities. That being stated, these venues are then teeming with possibilities to park and fly others with similar interest. It might then be this type of breeze to locate a person, whether of the identical or opposite gender, to click with. Personal enrichment and possibly even romantic associations could flourish.

Researches also says popular occasions for example ski and tennis competitions are very well-took part in by baby seniors. Simultaneously that you?re enhancing your health, you could also possess the best middle age dating experience of these occasions. So plunge in each time a tournament is simply nearby.

Consequently, just about all aspects of living today are added to technology, more commonly online. But because of the social and political background of baby seniors, the current age is received with skepticism. On the other hand, you will find studies that demonstrate that lots of baby seniors are actually into online middle age dating. Incidents where maintain profiles in a number of internet sites.

Using social networking systems doesn?t always imply that you like a boomer would need to sacrifice your values. You are able to take advantage from the devices and technology to your benefit. Besides, fundamental essentials best means today of interacting and creating personal connections to various types of people around the world. Essentially, your ultimate goal to attempt middle age dating is growing rapidly just made simpler. You might also need the final say whether you may be determined through the technology or else.

As being a baby boomer is really a pride by itself when you are targeted with wealthy understanding and understanding of your surroundings. Explore the middle age dating scene as though it is among the multifaceted encounters you have undergone to be able to are more fit in most facets of your existence.

Source: http://relationships-dating-for-boomers.chailit.com/the-infant-boomer-singles-scene.html

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Saturday, February 25, 2012

The Teaching and Research Blog: Technology: Communication ...

My brother and I were talking about technological change yesterday.?How time changes relationships between people! Technologies create more ways of doing and more technologies with which we, the people can have relationships. In general, the more communicative technologies we possess, the more convenient communication becomes and the less relational commitment, the lower the risk, and trust, in communicating.?

For example, about technologies and time in general, with more ways of doing at our disposable, there are, in fact, more distractions in our lives. Indeed, we have more reasons to be less punctual and more ways to convey our lack of punctuality. With mobile phones and instant messaging, we can, in fact, tell someone we will be late, and because we have these means, this gives us more reason to be late, we believe! We de-emphasize the need for punctuality, the importance of committing time and discipline in relationships. Is the trade between relational commitment and relational convenience worth it? That depends on your beliefs, values and assumptions about what is important in human relationships: accessing them; or showing you care about them.?

Communicative technologies can enhance and deepen human relationships by giving us access to relationships and providing different means by which to deepen these relationships. At the same time, they are no substitute for meeting someone in person, to see all that person's eyes, face and body, to hear that person's voice and of course, possibly to feel that person's touch. New technologies cannot replicate well, yet, this primordial, most significant human relationship communicative technology -- the face to face meeting. Perhaps the more we use other communicative technologies, thereby using less this face to face technology, the more shallow our relationship building and communication becomes. We become more superficial in our actions and thoughts if we, our being, are rendered into no more than words, even with emoticons.

Ultimately, myriad communicative technologies reduce the commitment which comes with the face to face encounter. More means to be less punctual. More means by which to make communication less exclusive -- that is, when you meet someone face to face, you should have your interlocutors attention in the same way that your interlocutor has your attention with eye contact, backchanneling and other responses; in contrast, you can instant message twenty people at the same time and likewise, even while video conferencing with someone, you can still do other things, unbeknowst to your partner in fact. Of course, even in face to face encounters, people can let others have a stronger immediate relationship with the technology than the other interlocutor. It may not be strange to see someone talking to another person while the other person is busying typing and staring into a screen. I find that strange and insensible. But maybe this will become more acceptable to me and others as our beliefs, values and assumptions about technology and relationships change -- and chip.?

The great danger for our society is that people grow up using communicative technologies to mediate human relationships without knowing what deep human relationships can be and what they should entail: a generation that texts may not ever appreciate how instant messaging during, at and for dinner is not a substitute for meeting someone in person for dinner. That the relationships we establish by meeting face to face may be more significant than the relationships that are primarily if not exclusively mediated by other communicative technologies. This generation may be able to "get more done in their human relationship," but they may be less committed and more superficial in their human relationships.?

Finally, I position myself in the relationship-first camp. My primary relationships are with people and not with technology. Technology is no more than a means to establishing and deepening human relationships in my life. I do not use technology for technology's sake; nor do I establish relationships and communicate for the sake of technological practice. My primary communicative technology is the face to face encounter.

Source: http://misterwoo.blogspot.com/2012/02/technology-communication-convenience.html

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Italian Renaissance Humanism In Art | NY Essay

By admin on February 23, 2012

The Renaissance, as defined in Merriam-Webster=s dictionary, is the transitional movement in Europe between medieval and modern times beginning in the 14th century in Italy, lasting into the 17th century, and marked by a humanistic revival of classical influence expressed in a flowering of the arts and literature and by the beginnings of modern science. Many dramatic changes occurred during this time in the fields of philosophy, literature, and art. New emphasis was placed on enjoying life and the world around man, and talented individuals sought self-gratification through art and philosophy (Vary). In Italy, the Renaissance presented through literary and art themes a new humanistic conception of man. The rise of the Medici family also held a great role in the sponsorship of the arts.

Humanism was considered to be the most significant intellectual movement of the Renaissance. As its name implies, humanism was a philosophy that was characterized by its blending of the concern of the We write better ! Get Free Quote or Order now!

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Source: http://nyessay.com/philosophy/italian-renaissance-humanism-in-art/

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Friday, February 24, 2012

Newly approved drug for metastatic melanoma nearly doubles median survival

ScienceDaily (Feb. 22, 2012) ? Researchers from UCLA's Jonsson Comprehensive Cancer Center, together with scientists from 12 other sites in the United States and Australia, report for the first time that a newly approved drug for patients with metastatic melanoma nearly doubles median survival times, a finding that will change the way this deadly form of skin cancer is treated.

The data comes from an international Phase II study of Zelboraf that included 132 patients followed for at least one year.

Patients with this advanced form of melanoma that has spread to other organs typically survive about nine months. Patients taking Zelboraf, which blocks a mutated BRAF protein, survived an average of 15.9 months, said study senior author Dr. Antoni Ribas, a professor of hematology/oncology and a researcher at UCLA's Jonsson Cancer Center.

"This study shows that Zelboraf changes the natural history of this disease," Ribas said. "This data is beyond what I would have expected. We're seeing a significant number of patients with durable responses to the drug, and that the whole group of treated patients is living longer. These results tell us that this drug is having a very big impact, and this changes the way we treat metastatic melanoma."

The study appears Feb. 23, 2012 in the peer-reviewed New England Journal of Medicine.

About 50 percent of patients with metastatic melanoma, or 4,000 people a year, have the BRAF mutation and can be treated with Zelboraf, a pill taken twice a day, Ribas said. Of those, 53 percent have an objective response to the drug, meaning their tumors shrink by more than 30 percent. An additional 30 percent of patients have tumor responses of lesser magnitude. Only 14 percent of patients with the BRAF mutation failed to respond to Zelboraf.

The drug represents a breakthrough in treating metastatic melanoma. Prior to this, 10 percent or less of patients with this advanced form of the disease responded to any of the available conventional treatments, Ribas said.

"We knew this drug would make the melanomas shrink in a large proportion of patients and that it worked better than chemotherapy," Ribas said. "We did not know that patients taking Zelboraf were living longer until now."

The main limitation with Zelboraf is that tumors eventually become resistant. But Jonsson Cancer Center researchers are studying this resistance and have uncovered several mechanisms by which the cancer gets around Zelboraf. Cancer center scientists currently are seeking agents to target those mechanisms, Ribas said.

For Louise Belley, 60, of Santa Ana, Zelboraf has allowed her to live much longer than her doctors initially predicted, and last June she was able to see her daughter graduate from college. Belley was diagnosed with metastatic melanoma in November of 2007. In June 2009, she was among the first people to get the drug when it was in Phase I studies at the Jonsson Cancer Center.

Her first CT scan in September 2009 after joining the trial -- nearly two and a half years ago -- was clear of any cancer, she said. Her scans remain clean today.

"At first I was devastated by my diagnosis, because I realized I was in a really bad place," Belley said. "But now I feel strongly that the chances are good that I will continue to be cancer free, and I plan to live every day to the fullest."

Zelboraf was approved by the U.S. Food and Drug Administration for use in metastatic melanoma in August of 2011. About 70,000 new cases of melanoma are diagnosed each year in the United States. Of those, 8,000 people will die of the disease.

"This trial shows a high rate of response to (Zelboraf) in patients with metastatic melanoma and activating BRAF mutations," the study states. "These results independently confirm the high response rate and response duration shown in a Phase I trial."

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The above story is reprinted from materials provided by University of California, Los Angeles (UCLA), Health Sciences, via Newswise. The original article was written by Kim Irwin.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

Journal Reference:

Jeffrey A. Sosman, Kevin B. Kim, Lynn Schuchter, Rene Gonzalez, Anna C. Pavlick, Jeffrey S. Weber, Grant A. McArthur, Thomas E. Hutson, Stergios J. Moschos, Keith T. Flaherty, Peter Hersey, Richard Kefford, Donald Lawrence, Igor Puzanov, Karl D. Lewis, Ravi K. Amaravadi, Bartosz Chmielowski, H. Jeffrey Lawrence, Yu Shyr, Fei Ye, Jiang Li, Keith B. Nolop, Richard J. Lee, Andrew K. Joe, Antoni Ribas. Survival in BRAF V600?Mutant Advanced Melanoma Treated with Vemurafenib. New England Journal of Medicine, 2012; 366 (8): 707 DOI: 10.1056/NEJMoa1112302

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://www.sciencedaily.com/releases/2012/02/120222204230.htm

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Spartacus Star Jai Courtney Joins Die Hard 5

die-hard-5-jai-courtney-bruce-willis-slice-2

20th Century Fox?s months long search for the lead in their upcoming fifth installment of the Die Hard franchise, A Good Day to Die Hard, has finally come to an end. Bruce Willis is back as John McClane, but a major character in the new film is McClane?s son. The studio finally landed on Jai Courtney, an up-and-comer who most recently starred on the Starz series Spartacus: Blood and Sand. The role was highly sought-after, with names like Aaron Paul, James Badge Dale, Paul Walker, and Milo Ventimiglia thrown around as contenders for the part. In the end, it was down to Courtney and Hunger Games star Liam Hemsworth. Hit the jump for more, including what to expect story-wise from A Good Day to Die Hard.

die-hard-5-jai-courtney Jack McClane is described as someone who may be even more of a hardass than his father (not possible). The story finds the two working together ?to keep each other alive and the world safe for democracy? despite their differences. John Moore (Max Payne) is set to direct, and the action this time around takes place in Moscow. I?m still not high on Moore as a director choice, but I think it?s smart to position someone to possibly take over the franchise/take it in a new direction once Willis bows out. Courtney will also be seen alongside Tom Cruise in One Shot and opposite Aaron Eckhart in I, Frankenstein. A Good Day to Die Hard is slated to open on February 14th, 2013.

Here?s the full press release, followed by an image from Courtney?s screen test with Willis:

LOS ANGELES (February 22, 2012) __ Following a global casting search spanning several months, Jai Courtney has nabbed the coveted role of John (Jack) McClane, Jr., the son of Bruce Willis? iconic action hero, in A GOOD DAY TO DIE HARD.

A GOOD DAY TO DIE HARD puts McClane on an international stage ? truly a NYC fish out of water in Moscow ? and introduces his estranged son Jack.? An apple that has not fallen far from the tree, Jack may even be more of a hardass than his father.? Despite their differences, they must work together to keep each other alive ? and the world safe for democracy.

The film begins production this April, for a February 14, 2013 release.

Courtney, studied drama at the Western Australian Academy of Performing Arts (WAAPA), where he graduated in 2008. Following graduation Courtney quickly landed?guest star roles on two hit Australian shows, Packed To the Rafters followed by All Saints. Later that year, Courtney won a Theatre Critics Award as Best Newcomer for his performance in The Turning for the Perth Theatre Company. In 2009 he landed the role of Varro in the international television hit, Spartacus: Blood and Sand. Fans of the show created an uproar over Varro?s death and to this day continue to lament about it on the many Spartacus fan sites and blogs. ?Last year, Courtney landed a starring role opposite Tom Cruise in One Shot, directed by?Christopher McQuarrie.

Source: http://www.rottentomatoes.com/m/1924593/news/1924593/

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Thursday, February 23, 2012

World Press Release ? Unsecured loans- Avail finance without ...

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> Press releases > Unsecured loans- Avail finance without risking your property
Wednesday, February 22nd, 2012

Are you not able to avail financial help due to lack of security? Need financial help instantly for meeting urgent needs? Unsecured loans are the best way to avail quick monetary aid. These are simple loans which offer you instant financial help without any irritating formalities. You can take unsecured loan for tenant for a number of purposes like consolidation of debts,

Higher education payments, Holiday enjoyment, Car purchase etc.

Unsecured loans (http://www.fastunsecuredloansforunemployed.co.uk) offers cash without any hassle of security. This financial scheme is helpful for the people like tenants or non-homeowners for availing quick cash aid. Under this plan you can get financial aid up to ?1500 for the period of 14 to 30 days. Your previous bad credit history does not restrict you to go for unsecured loan for tenant. You can avail unsecured loan for tenant irrespective of the following conditions Arrears, IVAs, Bankruptcy, Defaults in repayments.

It is the fact that unsecured loans come with higher interest rate as compared to any secured loan. This is the same with unsecured loan for tenant, as interest rates are a bit higher in this loan too. The loan application process is very fast and simple and it requires minimal paper work.

Internet can be used to make your search for unsecured loan. It will take no time to reach to a number of lenders while you search them online. You just have to fill an online application form with some details like name, address, loan amount, account number etc. The amount gets deposited in your account within 24 hours of approval.

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Source: http://www.worldpressrelease.org/?p=29146

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Wednesday, February 22, 2012

Home Equity Loans - IdeaMarketers.com

There are many different mortgage products available for different income levels and credit scenarios. You choose the one that suits your requirements the best. Home equity loans are now becoming increasingly popular. Banking institutions have some good re- financing plans to suit customer's needs. Home equity loan refers to the loan where the equity in the borrower's home is taken as the collateral for the loan. You can see that it brings down the actual home equity and creates security to the house of the borrower.

Types of home equity loan

There are two types of home equity loans, HELOC and HEL. Here the security is the value of the buyer's house and so, they are both called second mortgages. HELOC refers to Home Equity Line of Credit. HELOC has an adjustable interest rate and it is a revolving credit loan.

The buyer has the freedom to select hoe often and when to borrow against his home equity. It is an open end loan and the lender sets an initial limit to the line of credit based on certain factors. You can make use of this loan when you need it. HEL or home equity loan is the regular loan where you borrow a fixed amount of money for a fixed time period and at fixed interest rate.

For what kind of expenses can you borrow home equity loans?

You can get home equity loans when you have to pay for unavoidable expenses that are big. You can manage expenses like home repairs, renovations, investing in an another property, college tuition payments, credit card debt consolidation, mortgage refinancing, investment in mutual funds and shares, education, etc.

You do not have to worry about additional collateral as here your home equity serves that purpose. You need to be careful when you are opting for home equity loan. Ensure that you are using it only to pay some necessary expenses. Remember that your home is used as the security. If you cannot make payments on time, you are putting your home at risk.

Some factors to consider when borrowing home equity loan

See that your credit score is good. It is one of the ways the lender can analyze how you manage your debts, expenses and funds. See that you have not had a situation of bad credit because this can lower chances of your loan getting approved. It also limits the kind of benefits that you can get by the home equity loan. Bad credit scores also lead to lesser financing for the same home and higher rates of interest.

See that you have all the proofs that are required to grant you the loan. Make sure you have all the necessary documents ready with you. Typically, you might be asked to show your identity proof and to give a statement of advice from a financial planner or an accountant when it comes to home equity loans. You should provide a copy of the sales contract or a letter from the conveyancer, if you are using the fund to purchase real estate.

Keywords: finance, mortgage, real estate, home equity loans, debt consolidation, debt, equity loans, loans,

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Lacrosse hits the road in search of first win | Sports & Recreation ...

Sorry, Readability was unable to parse this page for content.

Source: http://arlington.firstcoastnews.com/news/sports-recreation/73832-lacrosse-hits-road-search-first-win

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Tuesday, February 21, 2012

Powerful Explanations Of GPS Tracking Devices | Dating Advice ...

There is a growing interest in satellite technology. It has many applications that will alter the way that society conducts business. A company can use electronic devices to track inventory on any location on Earth. There are many people that have doubts about it, but continuous results have demonstrated that assets can be protected more effectively. As enthusiast continue to read, they will discover ways to use GPS tracking.

Commodities are shipped across the world on planes, trains and trucks. They are packaged and tied down to pallets to prevent damage. In order to protect the loads from hazards, shippers can use electronic devices. These are tools, which have the ability to track products in transit to prevent theft.

The automobile industry also depends on semi trucks to transport their products. Car haulers are best suited for this purpose due to their large load capacity and safety features. Unfortunately, they lack the means to prevent theft from hijackers. Once the freight is stolen, it may never be located. Shippers can fight back by installing small boxes that contain electrical components designed to transmit the freight?s location. This will allow the authorities to locate the culprits in no time.

Hiking is a wonderful hobby that is pursued by many backpacking enthusiast. They enjoy walking and observing the natural wonders of the world, but also are vulnerable to many hazards. These include adverse weather, animal attacks, falls and sickness. By immersing themselves in solitude, they lack communications with the outside world. A electronic device could transmit their location in the event of a emergency.

The intelligence agencies are tasked with collecting data from various countries in the name of national security. They employ agents, which conduct surveillance operations frequently. Their jobs can become a lot easier when they use satellite technology for the missions.

Racing is a exciting sport that attracts many spectators. The vehicles operate at a high level of performance and the tracks are usually paved. As the drivers make their way to the ends of the track, they may not be visible to officials. In order for them to determine if someone is cheating, they would need to know the locations.

Some people have criminal tendencies and have to face the consequences when they get caught. They sometimes have to spend time at their homes on house arrest or they could end up in more trouble. Law enforcement officers typically use ankle bracelets to make sure the individuals to do not try to flee from the residence. There is also no way for the device to be tampered with because it would be detected.

Society is evolving on a technological level at a fast rate. The satellites have made a large contribution to the development of electronic monitoring devices. There are many applications for them, which include preventing theft, espionage, house arrest, racing and backpacking. They also come in passive or active systems, but hybrids offer more flexibility. Enthusiast can learn more about these gadgets by studying GPS tracking equipment.

We are a company with vast experience in GPS fleet management, mobile data communications, fleet management and other communication management.

Source: http://datingadvicesingles.com/love/?p=48061

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Rufus Wainwright's 'Prima Donna' Has U.S. Premiere At The Brooklyn Academy Of Music (PHOTOS)

Nearly five years after a dropped deal with the Metropolitan Opera and three years after it premiered at the Palace Theatre in Manchester, England, Rufus Wainwright's first opera, "Prima Donna," landed at the Brooklyn Academy of Music in New York for its U.S. premiere Sunday afternoon. Angelica Houston, Lou Reed and Laurie Anderson could be spotted in the audience, alongside Wainwright himself, who looked sharp in a bedazzled toreador outfit.

The opera, written in French with English subtitles (and co-written by Bernadette Colomine), follows an acclaimed, but forgotten soprano, Regine Saint Laurent, who is preparing a return to the stage in the role she was known for, "Alienor d'Aquitaine." Regine is panic-stricken about reprising Alienor, convinced her voice is forever gone. In her somewhat deranged state, she latches on to a young journalist who is all too ready to lavish attention on her.

The opera received mixed reviews when it ran in England, with a completely different cast from the one on stage stateside. While the opera lacked a key emotional moment that could have made it great, this viewer found it worth the two-hour runtime -- highlights included the shifting backdrops, the maid's (Kathryn Guthrie Demos) solo performance -- which outshone any other single moment on stage -- and a subtle, effective ending. The plot itself takes a while to build, but picks up in the second half, when it delivers a few amusing tricks. At times, it's reminiscent of "The Artist," another film that shows the depression, anxiety and irrational behavior that ensue when a star falls.

Check out photos of Wainwright making the rounds Sunday afternoon, and visit BAM's website for ticket information.

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(VIDEO)","slideshow_id":"209659","vertical":"culture"},{"entry_id":"1267161","entry_url":"http:\/\/www.huffingtonpost.com\/2012\/02\/09\/music-documentaries_n_1267161.html","content_type":"video","image_url":"gadgets\/slideshows\/208701\/slide_208701_681284_small.jpg","thumbnail_url":"gadgets\/slideshows\/208701\/slide_208701_681284_small.jpg","title":"The Best Music Documentaries Ever: Michael Rapaport Picks His Favorites","slideshow_id":"208701","vertical":"culture"}]

Watch the trailer for the Sundance Channel documentary, "Rufus Wainwright: Prima Donna":

Source: http://www.huffingtonpost.com/2012/02/20/rufus-wainwright-prima-donna_n_1289064.html

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